Plucky Duck and Hamton J. Pig

The characters in the American animated television series Tiny Toon Adventures and its reboot Tiny Toons Looniversity were created by animator Tom Ruegger. The series chronicles the adventures of Buster Bunny, Babs Bunny and their various friends in the fictional city of Acme Acres. Most of the characters are anthropomorphic animals and humans based on the Looney Tunes characters.

Tiny Toon Adventures features the voices of Charlie Adler, John Kassir, Tress MacNeille, Joe Alaskey, Don Messick, Kath Soucie, Gail Matthius, Maurice LaMarche, Danny Cooksey, Cree Summer, Candi Milo, Rob Paulsen and Frank Welker, while Tiny Toons Looniversity also features the voices of Eric Bauza, Ashleigh Crystal Hairston, David Errigo Jr. and Marieve Herington. Most one-off and background characters in each series are voiced by Jim Cummings, Greg Burson, Noel Blanc, Stan Freberg. In addition to the series' regular cast, various celebrities from a wide range of professions have voiced guest characters and recurring roles.

Buster Bunny (voiced by Charlie Adler in 1990–1992 of the original series and the cancelled 2002 video game, John Kassir in 1992–1999 of the original series, Eric Bauza in Tiny Toons Looniversity ) is the leading main character of the show. Buster is a young blue-and-white male bunny rabbit with a red shirt (red hoodie in the reboot) and white gloves, and is Babs' best friend. In the last episode, It's a Wonderful Tiny Toon Christmas Special, Babs states that Buster is her boyfriend. Bugs Bunny is Buster's mentor. Adler voiced Buster in the cancelled video game Tiny Toon Adventures: Defenders of the Universe. Buster is based on the Chuck Jones version of Bugs Bunny.

In the Looniversity reboot, Buster is Babs' twin brother. Given the many different aspects of their personality traits, "Adventures" Buster and "Looniversity" Buster are practically two different characters. In "Extra, So Extra", his middle name is "Filmore."